JANUS KINASE (JAK) INHIBITORS

What are they?

Block Janus kinase enzymes of immune system that contribute to inflammation, prescribed when topical treatments alone are not working.1,2

How do they work?

By enzymes contributing to inflammation, they reduce symptoms such as itching and skin lesions.1,2

How often do you use them?

Based on doctors advise1

How are they administered?

Orally or topically1,2

What are the possible side effects?

Increased cholesterol, skin infections, URTI, headaches.1 Monitoring may be necessary.1,2

References:

  1. Rodrigues, M.A. & Torres, T. (2020). The changing landscape of atopc dermatitis – focusing on JAK inhibitors. Eur Ann Allergy Clin Immunol. 52(1):45-48. http://www.eurannallergyimm.com/cont/journals-articles/769/volume-n-changing-landscape-atopic-dermatitis-3461allasp1.pdf
     
  2. European Medicines Agency. (2020). “New oral treatment for moderate to severe atopic dermatitis”, https://www.ema.europa.eu/en/news/new-oral-treatment-moderate-severe-atopic-dermatitis (Accessed July 29, 2022)

MAT-MY-2201022 (10/22)

Health information contained herein is provided for general educational purposes only. Your healthcare professional is the single best source of information regarding your health. Please consult your healthcare professional if you have any questions about your health or treatment.